Perhaps the most well-known strategy when it comes to Three-Card Poker is to make a play wager if you have Queen-6-4 or better (Q-6-4). This can make for a very enjoyable experience in that it is relatively straightforward to play, but hard to master. Yet unlike most, Three-Card Poker simplifies the game instead of adding complex rule systems. There is a world of poker variations out there, each with its own strategies and tactics.